Mind the Gap atlas
Central centrifugal cicatricial alopecia (CCCA) on Black skin
Key cue: Slowly expanding hair loss from the crown outward, with smooth shiny scalp. Primarily affects Black women; early dermatology care preserves follicles.
Central centrifugal cicatricial alopecia (CCCA) is the most common form of scarring alopecia in Black women, affecting an estimated 6-15% of Black adult women in US community studies (Olsen EA., Arch Dermatol 2011). It begins at the crown/vertex and spreads centrifugally. Because it is scarring, early diagnosis is the difference between preserving and permanently losing hair.
What it actually looks like
Textbook says
Textbook: central/vertex scarring alopecia with smooth, shiny scalp, loss of follicular openings, and gradual centrifugal expansion. Patients often report mild tenderness, itch, or burning in the affected area early on. Histology: premature desquamation of the inner root sheath, perifollicular inflammation, eventual follicular destruction and fibrosis.
On Black skin
CCCA is a primarily Black-women's disease; the skin-of-colour literature is where most of the evidence comes from:
- Early CCCA shows widening of the part at the crown, shorter/broken hairs in the central scalp, and subtle scalp changes — often before obvious hair loss. This is the window for effective treatment.
- Loss of follicular openings (a smooth, shiny scalp where follicles should be) is a late and irreversible sign. On Black skin this can be subtle — compare affected area to the occipital scalp (normal follicles visible).
- Tenderness, itch, or burning of the crown/vertex is common and often the chief complaint — don't dismiss 'tender scalp' in a Black woman as just haircare irritation.
- Tight hairstyles (braids, weaves, relaxers) were historically implicated but are no longer believed to be the primary cause — CCCA has genetic components (PADI3 gene variants, Malki et al. NEJM 2019) and an inflammatory pathophysiology. Avoiding extreme traction remains reasonable.
- Treatment: first-line topical and intralesional corticosteroids, oral doxycycline or minocycline (anti-inflammatory effect), minoxidil (topical or oral), and — in refractory cases — hydroxychloroquine or methotrexate. Hair transplant is possible only once disease is quiescent and requires an experienced SOC surgeon.
- Traction alopecia — a related but distinct hairline-retraction pattern from tight hairstyles — can coexist and is reversible if caught early.
What to look for
- Widening of the part at the crown or visible scalp on top of the head where there used to be full hair.
- Tender, itchy, or burning scalp at the vertex/crown.
- Short, broken hairs, or hairs that are thinner than surrounding hair.
- Shiny, smooth-looking skin on the scalp where follicles should be visible.
- Gradual spread over months to years from the crown outward.
When to seek care
See a dermatologist with expertise in hair disorders and Black scalp as soon as possible. A scalp biopsy confirms CCCA and rules out other scarring alopecias (discoid lupus, lichen planopilaris, frontal fibrosing alopecia). Early treatment preserves remaining follicles. Skin of Color Society maintains a referral list; the NAHRS also lists qualified dermatologists.
Common misdiagnosis
Early CCCA is frequently misdiagnosed as seborrheic dermatitis, traction alopecia, androgenetic alopecia, or 'breakage from relaxers'. Each of these has different treatment. A scalp biopsy (small 4 mm punch) is the gold-standard differentiator and should not be delayed; untreated CCCA is irreversible.
See it for yourself — curated external imagery
We don't host clinical photos here. The links below go to peer-reviewed or open-access sources (Mind the Gap, DermNet NZ, PubMed Central, and similar). Each opens in a new tab.
- DermNet NZ — Central centrifugal cicatricial alopecia — image set including early and late disease.
- Skin of Color Society — CCCA — patient-facing education.
- PMC — CCCA clinical review (open access).
- Skin of Color Society directory for finding a qualified dermatologist.
References
- Olsen EA, Callender V, McMichael A, et al. Central hair loss in African American women: incidence and potential risk factors. J Am Acad Dermatol. 2011;64(2):245-52. PMID: 21030101.
- Malki L, Sarig O, Romano MT, et al. Variant PADI3 in central centrifugal cicatricial alopecia. N Engl J Med. 2019;380(9):833-841. PMID: 30763140.
- Callender VD, McMichael AJ, Cohen GF. Medical and surgical therapies for alopecias in Black women. Dermatol Ther. 2004;17(2):164-76. PMID: 15113284.
- Olsen EA, Bergfeld WF, Cotsarelis G, et al. Summary of North American Hair Research Society (NAHRS)-sponsored Workshop on Cicatricial Alopecia. J Am Acad Dermatol. 2003;48(1):103-10. PMID: 12522380.
Medical disclaimer
Educational content only. This is not a substitute for in-person evaluation. If you are worried about yourself or someone you love, see a clinician — and if you are concerned about an emergency sign described here, call 911 or your local emergency number. We do not host clinical imagery; the external references are for reader self-education and are not owned by or affiliated with Black Health.