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Glossary

GLP-1 agonist

Also known as: GLP-1 receptor agonist, glucagon-like peptide-1 agonist

Medically reviewed, last updated

GLP-1 agonists are a class of injectable (and some oral) medications that mimic the gut hormone glucagon-like peptide-1. They slow gastric emptying, suppress appetite, and improve glycemic control. Common GLP-1 agonists include semaglutide (Ozempic, Wegovy), tirzepatide (Mounjaro, Zepbound), and liraglutide (Saxenda, Victoza).

Originally approved for type 2 diabetes, GLP-1 agonists are now widely used for chronic weight management and have shown secondary benefits for cardiovascular risk reduction. Black patients are under-represented in the registration trials, though enrollment in newer studies has improved. See semaglutide.

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Medical Disclaimer

This glossary entry is for informational and educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition.