HIV testing in South Carolina — where to get tested, free options, what to expect
The number
790 new HIV diagnoses in South Carolina in 2022, 71% among Black residents — all preventable with timely testing and linkage to PrEP.
Ryan White Part B
South Carolina Department of Public Health, Bureau of HIV/STD Services
State ADAP
South Carolina AIDS Drug Assistance Program
Income cap 550% FPL
State PrEP-DAP
Not operated; federal Ready Set PrEP applies
Where to get tested in South Carolina
20,100 people are living with HIV in South Carolina, and 71% of new diagnoses in 2022 were among Black residents. Getting tested is the first step — the CDC recommends at least one HIV test for every adult 13-64, and annual testing for anyone sexually active with more than one partner or injecting drugs. Rapid tests return results in about 20 minutes from a fingerstick; laboratory tests take a few days but catch infections sooner after exposure (as early as 10 days with a nucleic-acid test).
Where to test for free in South Carolina: every county health department runs an STI / HIV testing clinic, and South Carolina Department of Public Health, Bureau of HIV/STD Services contracts with community-based organizations to operate walk-in rapid testing with evening and Saturday hours. No ID or insurance is required at these sites. Confidentiality is protected — state law requires public-health HIV testing results to stay out of your medical record unless you authorize release, and anonymous testing (no name collected) is available at most community sites.
What to expect: a pre-test conversation about risk and what a positive result would mean, the test itself (either fingerstick or blood draw), and post-test counseling. If the rapid test is reactive, the counselor draws blood for a confirmatory Western blot or antigen/antibody test. If you're positive, you'll be linked to a Ryan White Part C clinic for same-week HIV primary care and ADAP enrollment if you qualify by income.
The South Carolina HIV info line is 1-803-898-0749; staff can point you to the nearest free testing site, schedule PrEP, and help you navigate insurance or no-insurance options. Long-time Black residents name MUSC Ryan White Clinic and Palmetto Community Care as the local institutions that show up consistently — both are listed below.
MUSC Ryan White Clinic. The MUSC Ryan White Clinic in Charleston is South Carolina's largest Ryan White Part C grantee, serving about 2,400 people living with HIV across the Lowcountry; MUSC co-runs the Palmetto State's EHE Charleston plan with Roper St. Francis Healthcare.
Palmetto Community Care. Palmetto Community Care in North Charleston (formerly Lowcountry AIDS Services) is the Ryan White Part B case-management contractor for the Lowcountry region, with a dedicated Black-women-focused prevention program and the state's highest-volume community rapid-testing van.
For Black families in South Carolina
The South carries the heaviest HIV burden in the country: Black Southern residents make up roughly 14% of the U.S. population but account for more than half of new Black HIV diagnoses nationally. In South Carolina, 71% of new 2022 HIV diagnoses were among Black residents. That figure reflects unequal access to testing more than underlying risk: a Black person in South Carolina waits longer for an HIV diagnosis on average than a white peer, and late diagnoses translate directly into later treatment starts and worse outcomes. The community organizations listed below — particularly those flagged as Black-community anchors on the directory — operate rapid-testing sites specifically designed to close that wait-time gap.
Named HIV testing + PrEP sites in South Carolina
MUSC Ryan White Clinic — Charleston
Charleston, SC • 1-843-792-3484
Palmetto Community Care — North Charleston
North Charleston, SC • 1-843-747-2273
SC Department of Health and Environmental Control — Richland County Health Department
Columbia, SC • 1-803-576-2997
Palmetto AIDS Life Support Services (PALSS) — Columbia
Columbia, SC • 1-803-779-7257
AIDS Upstate — Greenville
Greenville, SC • 1-864-250-0607
Where to get help in South Carolina
- South Carolina HIV info line: 1-803-898-0749 — staff can find the nearest free testing site, schedule PrEP, or help enroll you in ADAP.
- South Carolina Department of Public Health, Bureau of HIV/STD Services landing page: https://dph.sc.gov/diseases-conditions/hiv-aids.
- Federally Qualified Health Centers in South Carolina: every FQHC offers sliding-scale HIV testing and has certified application counselors on staff. See our FQHC directory for the state at /clinics/sc/.
- State health data for South Carolina: for state-level HIV mortality, maternal health, and life-expectancy context by race, see /health/south-carolina/.
- South Carolina Medicaid: Medicaid is the largest single payer of HIV care in most states. See /medicaid/south-carolina/ for eligibility + enrollment.
- CDC NPIN testing-site finder: gettested.cdc.gov accepts a zip code and returns every free + low-cost HIV testing site within 50 miles.
References & primary sources
- South Carolina Department of Public Health, Bureau of HIV/STD Services: https://dph.sc.gov/diseases-conditions/hiv-aids.
- CDC HIV Surveillance Report 2022: cdc.gov/hiv/library/reports/hiv-surveillance.html. Source for state-level new diagnoses and race-stratified counts.
- HRSA HIV/AIDS Bureau, Ryan White HIV/AIDS Program grantee list: ryanwhite.hrsa.gov/grants/part-b.
- NASTAD ADAP Monitoring Project 2024 Annual Report: nastad.org/adap-monitoring-project. Source for ADAP income cap + enrollment + PrEP-DAP data.
- AIDSVu state profile: aidsvu.org/state/south-carolina/.
Data refreshed: