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First trimester · Pregnancy week by week

Week 12 of pregnancy

Baby is the size of a lime. About 2.10 inches, 14g.

By week 12, you've reached the end of the first trimester. Per USPSTF 2021, low-dose aspirin from week 12 reduces preeclampsia risk by ~25% in high-risk patients — including, in the U.S. context, Black patients. Source

What's happening with the baby

The fetus has all major organs formed. Reflexes develop — fingers can curl, eyes are sealed shut, the fetus practices breathing. The intestines move into the abdomen. The face has a more human appearance.

What's happening for you

Many women feel a noticeable improvement in nausea and energy. The uterus is the size of a grapefruit. Some women see early bump showing. Mood often stabilizes as hormones plateau.

Common (normal) symptoms this week

Improved nausea, returning energy, mild round-ligament pain, increased vaginal discharge, occasional headaches, breast growth, slight bump showing.

Call your OB or 911 if

  • Severe abdominal or one-sided pelvic pain with bleeding — possible ectopic pregnancy.
  • Heavy vaginal bleeding (soaking a pad in an hour) with cramping.
  • Fainting, severe dizziness, or shoulder-tip pain — ectopic with internal bleeding is an emergency.
  • Fever over 101°F with chills or pelvic pain.
  • Severe vomiting that prevents keeping any fluids down for 24+ hours (hyperemesis).

Why this week matters for Black families

By the end of the first trimester, several decisions matter for Black families. (1) Whether to do first-trimester genetic screening (NIPT). The Bonus uptake rate for NIPT is lower for Black patients, and the literature documents that providers offer it less often — if you want it, ask explicitly. (2) Documenting baseline blood pressure. Pre-existing chronic hypertension is more common in Black women and changes the entire prenatal-care plan. (3) Asking about low-dose aspirin for preeclampsia prevention. Per the USPSTF 2021 recommendation, Black patients are in the high-risk category for which aspirin from 12 weeks onward is supported by RCT evidence.

What to do this week

Start low-dose aspirin (81 mg daily) if your OB has prescribed it for preeclampsia prevention. If not discussed, ask about it. End-of-first-trimester ultrasound and bloodwork are typical. The next visit is usually around week 16 — bring a list of any symptoms you've had so far, however minor. Begin documenting baseline blood pressure if you're on the higher-risk side.

References

Last medically reviewed: .

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