PrEP in Wyoming — pre-exposure prophylaxis, who qualifies, how to start
The number
Wyoming does not operate a state PrEP-DAP; the federal Ready, Set, PrEP program covers medication for eligible uninsured residents.
Ryan White Part B
Wyoming Department of Health, Communicable Disease Unit
State ADAP
Wyoming AIDS Drug Assistance Program
Income cap 300% FPL
State PrEP-DAP
Not operated; federal Ready Set PrEP applies
How to start PrEP in Wyoming
Pre-exposure prophylaxis (PrEP) is a daily pill (Truvada, Descovy) or every-two-months injection (Apretude) that prevents HIV in people who don't have HIV. Taken as prescribed, daily-pill PrEP reduces the risk of sexually transmitted HIV by about 99% and the risk from injection-drug sharing by about 74%, per CDC. In Wyoming, PrEP is available through primary-care providers, FQHCs, LGBTQ+ community health centers, and Ryan White Part C clinics — you do not need to see an HIV specialist to start.
To qualify for PrEP you need a recent negative HIV test (or one done the same day), a baseline labs panel (kidney function, hepatitis B, STIs), and a prescriber visit. Follow-up is every three months for a repeat HIV test and medication refill. Most insurance including Medicaid covers PrEP with zero out-of-pocket under the USPSTF Grade A preventive-services rule. The drug manufacturers (Gilead, ViiV) operate patient-assistance programs for anyone without insurance.
Wyoming does not operate a state-funded PrEP Drug Assistance Program; residents rely on the federal Ready, Set, PrEP program (getyourprep.com) for medication coverage, Gilead Advancing Access or ViiV Connect for the drug copay, and the USPSTF Grade A preventive-services rule for clinic visits and labs (required zero-cost-share under the ACA). The state HIV program line is 1-307-777-7953 for a PrEP clinic referral.
Black PrEP uptake nationally lags sharply — a 2023 AIDSVu analysis found that Black Americans account for 42% of new HIV diagnoses but only 14% of PrEP users. Long-time Black residents name Wyoming Health Council and Cheyenne Regional Medical Center Infectious Disease Clinic as the local institutions that show up consistently — both are listed below.
Wyoming Health Council. The Wyoming Health Council in Casper is the state's Ryan White Part B case-management contractor, operating rapid testing at six clinic sites across Natrona, Laramie, and Fremont counties and the state's only dedicated HIV peer-navigation program.
Cheyenne Regional Medical Center Infectious Disease Clinic. The ID Clinic at Cheyenne Regional Medical Center is Wyoming's primary HIV specialty clinic and Ryan White Part C grantee, covering eastern Wyoming through a telehealth partnership with the University of Colorado's Denver Health ID Clinic.
For Black families in Wyoming
PrEP uptake among Black Americans lags sharply — AIDSVu's 2023 PrEP-to-Need ratio analysis puts the Black PrEP ratio at roughly one-eighth the white ratio. In Wyoming specifically, with 12% of new 2022 diagnoses among Black residents, closing that PrEP gap is the single highest-leverage prevention move. Black-led HIV organizations in the state run PrEP-specific navigation programs that match you with a prescriber, handle benefits coordination, and keep you in the three-month follow-up rhythm.
Where to get help in Wyoming
- Wyoming HIV info line: 1-307-777-7953 — staff can find the nearest free testing site, schedule PrEP, or help enroll you in ADAP.
- Wyoming Department of Health, Communicable Disease Unit landing page: https://health.wyo.gov/publichealth/communicable-disease-unit/hivaids/.
- Federally Qualified Health Centers in Wyoming: every FQHC offers sliding-scale HIV testing and has certified application counselors on staff. See our FQHC directory for the state at /clinics/wy/.
- State health data for Wyoming: for state-level HIV mortality, maternal health, and life-expectancy context by race, see /health/wyoming/.
- Wyoming Medicaid: Medicaid is the largest single payer of HIV care in most states. See /medicaid/wyoming/ for eligibility + enrollment.
- Federal Ready, Set, PrEP: getyourprep.com — no-cost PrEP medication for people without insurance.
- CDC NPIN testing-site finder: gettested.cdc.gov accepts a zip code and returns every free + low-cost HIV testing site within 50 miles.
References & primary sources
- Wyoming Department of Health, Communicable Disease Unit: https://health.wyo.gov/publichealth/communicable-disease-unit/hivaids/.
- CDC HIV Surveillance Report 2022: cdc.gov/hiv/library/reports/hiv-surveillance.html. Source for state-level new diagnoses and race-stratified counts.
- HRSA HIV/AIDS Bureau, Ryan White HIV/AIDS Program grantee list: ryanwhite.hrsa.gov/grants/part-b.
- NASTAD ADAP Monitoring Project 2024 Annual Report: nastad.org/adap-monitoring-project. Source for ADAP income cap + enrollment + PrEP-DAP data.
- AIDSVu state profile: aidsvu.org/state/wyoming/.
- CDC PrEP guidelines, 2021 update: cdc.gov/hiv/clinicians/prevention/prep.html.
Data refreshed: