Drug class
Used for
Fluoxetine
SSRIBrand: Prozac, Sarafem
Fluoxetine is primarily metabolized by CYP2D6 (with contributions from CYP2C9 and 3A4). CYP2D6 allele distributions vary by ancestry, but variant effects on …
View guideSertraline
SSRI (selective serotonin reuptake inhibitor)Brand: Zoloft
SSRIs as a class have more complex race-specific evidence than cardiovascular drugs. Three themes matter:Response rates. Post-hoc analyses of STAR*D (Lesser et …
View guideVenlafaxine
Serotonin, norepinephrine reuptake inhibitor (SNRI)Brand: Effexor, Effexor XR
Venlafaxine is metabolized to its active metabolite desvenlafaxine (Pristiq) by CYP2D6. CYP2D6 poor metabolizers, more common in some Black populations for certain …
View guideNo medications match your search.